博士，西南大学特聘副教授

简历：

2018.1–2019.6    西南大学博士后

2011.9–2017.12 西南大学生物化学与分子生物学专业，硕博连读，理学博士

2007.9–2011.6   西南大学生物技术专业，本科，理学学士

主要科研领域与方向：

1. 蚕丝相关突变体的突变机理及应用研究

2.基于基因编辑技术，进行新型蚕丝创制

科学成就：

揭示了困扰研究学者80余年的家蚕裸蛹突变的突变基因及突变机理；首次阐释家蚕丝腺从眠期到龄期发育过程中的分子变化；目前已发表论文10余篇，多次受邀到英国牛津大学、英国谢菲尔德大学等国际知名研究机构参加学术会议并做报告。

代表性论文/论著：

1. Hu, W., Lu, W., Wei, L., Zhang, Y., Xia, Q.. Molecular nature of dominant naked pupa mutation reveals novel insights into silk production in Bombyx mori. Insect Biochem Mol Biol, 2019, 109, 52-62.

2. Hu, W., Chen, Y., Lin, Y., Xia, Q.. Developmental and transcriptomic features characterize defects of silk gland growth and silk production in silkworm naked pupa mutant. Insect Biochem Mol Biol, 2019, 111, 103-175.

3. Hu, W., Liu, C., Cheng, T., Li, W., Wang, N., Xia, Q. Histomorphometric and transcriptomic features characterize silk glands' development during the molt to intermolt transition process in silkworm[J]. Insect Biochem Mol Biol, 2016, 76: 95-108.

4. Liu, C*., Hu, W*., Cheng, T., Peng, Z., Mita, K., Xia, Q. Osiris9a is a major component of silk fiber in lepidopteran insects[J]. Insect Biochemistry and Molecular Biology, 2017.

5. Li, W., Cheng, T., Hu, W., Peng, Z., Liu, C., Xia, Q. Genome-wide identification and analysis of JHBP-domain family members in the silkworm Bombyx mori[J]. Mol Genet Genomics, 2016, 291(6): 2159-2171.

6. Chang, H., Cheng, T., Wu, Y., Hu, W., Long, R., Liu, C., Zhao, P., Xia, Q. Transcriptomic Analysis of the Anterior Silk Gland in the Domestic Silkworm (Bombyx mori) - Insight into the Mechanism of Silk Formation and Spinning[J]. PLoS One, 2015, 10(9): e0139424.

7. .Zhao, X., Liu, C., Li, Q., Hu, W., Zhou, M., Nie, H., Zhang, Y., Peng, Z., Zhao, P., Xia, Q. Basic helix-loop-helix transcription factor Bmsage is involved in regulation of fibroin H-chain gene via interaction with SGF1 in Bombyx mori[J]. PLoS One, 2014, 9(4): e94091.

联系地址：重庆市北碚区西南大学（南区）家蚕基因组生物学国家重点实验室，400716

E-mail：huwenbo2018@swu.edu.cn