胡文波
发布时间: 2018-03-24 20:40:25   作者:本站编辑   来源: 本站原创   浏览次数:



博士,博士后


简历:

2018.1–至今    西南大学博士后

2011.9–2017.12 西南大学生物化学与分子生物学专业,硕博连读,理学博士

2007.9–2011.6   西南大学生物技术专业,本科,理学学士

 

主要科研领域与方向:

1. 蚕丝相关突变体的突变机理及应用研究

2.基于基因编辑技术,进行新型蚕丝创制


科学成就:

揭示了困扰研究学者80余年的家蚕裸蛹突变的突变基因及突变机理;首次阐释家蚕丝腺从眠期到龄期发育过程中的分子变化;目前已发表论文10余篇,多次受邀到英国牛津大学、英国谢菲尔德大学等国际知名研究机构参加学术会议并做报告。


代表性论文/论著:

1.Hu, W., Liu, C., Cheng, T., Li, W., Wang, N., Xia, Q. Histomorphometric and transcriptomic features characterize silk glands' development during the molt to intermolt transition process in silkworm[J]. Insect Biochem Mol Biol, 2016, 76: 95-108.

2.Hu, W., Wei, L., Chen, Y., Wang, X., Ma, S., Zhang, Y., Liu, C., Xia, Q. C-terminal deleted fibroin heavy chain causes secretion deficiency and progressive degeneration in silkworm silk gland. (PloS Biology, submitted)

3.Liu, C*., Hu, W*., Cheng, T., Peng, Z., Mita, K., Xia, Q. Osiris9a is a major component of silk fiber in lepidopteran insects[J]. Insect Biochemistry and Molecular Biology, 2017.

4.Li, W., Cheng, T., Hu, W., Peng, Z., Liu, C., Xia, Q. Genome-wide identification and analysis of JHBP-domain family members in the silkworm Bombyx mori[J]. Mol Genet Genomics, 2016, 291(6): 2159-2171.

5.Chang, H., Cheng, T., Wu, Y., Hu, W., Long, R., Liu, C., Zhao, P., Xia, Q. Transcriptomic Analysis of the Anterior Silk Gland in the Domestic Silkworm (Bombyx mori) - Insight into the Mechanism of Silk Formation and Spinning[J]. PLoS One, 2015, 10(9): e0139424.

 6.Zhao, X., Liu, C., Li, Q., Hu, W., Zhou, M., Nie, H., Zhang, Y., Peng, Z., Zhao, P., Xia, Q. Basic helix-loop-helix transcription factor Bmsage is involved in regulation of fibroin H-chain gene via interaction with SGF1 in Bombyx mori[J]. PLoS One, 2014, 9(4): e94091.



联系地址:重庆市北碚区西南大学(南区)家蚕基因组生物学国家重点实验室,400716

E-mail:huwenbo2018@swu.edu.cn